The Respiratory Functional Genetics Laboratory at Brigham and Women’s Hospital, Harvard Medical School offers a full-time post-doctor position to study lipid and glucose metabolism in the respiratory disease. Interested and highly motivated candidates will be given the opportunity to participate in an innovative translational research on the cellular and molecular mechanisms of disease susceptible genes.

Post-doctoral Fellow

Our research group aims to determine the function of genes identified by genome-wide association studies (GWAS) mainly in respiratory diseases and shared common GWAS genes with metabolic traits. For this aim, we have developed a series of genetic deficient mouse lines targeting these GWAS genes. This new research fellow will perform in vitro and in vivo experiments to understand how these genes modulate metabolic changes thus determines disease susceptibility.

A successful candidate should have prior knowledge in studying metabolism with strong technical skills in molecular biology, cell biology. Fresh graduate students are encouraged to apply. This position requires strong motivation to work in a dynamic and challenging research area.

Post-doctoral Fellow

Our research group aims to identify functional variants within genome-wide association studies (GWAS) loci in respiratory diseases, primarily asthma and Chronic Obstructive Pulmonary Disease (COPD). This new research fellow will perform highly dynamic and innovative research to generate transcriptional regulatory networks in human airway epithelial cells under various conditions and will apply such data into understanding molecular mechanism by which genomics loci associated with COPD. He or she will also closely work with bioinformatics team and genetic scientists collaboratively to identify the candidate genes and causal variants in various GWAS loci in COPD.

A successful candidate should have prior knowledge in studying gene regulation, histone modification, chromatin structure, open chromatin and with strong technical skills in molecular biology, cell biology. This position requires strong motivation to work in a dynamic and challenging research area. Please submit inquires and applications to Dr. Anny Xiaobo Zhou, Ph.D. rexiz@channing.harvard.edu.

© 2017 - The Zhou Lab